Expression of the Late Cytomegalovirus (CMV) pp150 Transcript in Leukocytes of AIDS Patients Is Associated with a High Viral DNA Load in Leukocytes and Presence of CMV DNA in Plasma
نویسندگان
چکیده
منابع مشابه
Cytomegalovirus (CMV) DNA load is an independent predictor of CMV disease and survival in advanced AIDS.
The impact of cytomegalovirus (CMV) on human immunodeficiency virus type 1 (HIV-1) disease progression has been controversial. In this study, we sought to determine if CMV viral load is independent of HIV-1 viral load in predicting CMV disease and survival. Our findings indicate that in patients with advanced AIDS, CMV DNA load is an independent marker of CMV disease and survival and is more pr...
متن کاملCytomegalovirus (CMV) blood DNA load, CMV retinitis progression, and occurrence of resistant CMV in patients with CMV retinitis.
BACKGROUND The amount of cytomegalovirus (CMV) DNA in the blood (CMV load) may be a marker for detection of resistant CMV.METHODS. A total of 165 patients with AIDS and CMV retinitis had CMV load measurements (plasma and leukocyte) and cultures performed every 3 months; these measurements were correlated with CMV resistance to antiviral drugs and CMV retinitis progression (from masked readings ...
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ژورنال
عنوان ژورنال: The Journal of Infectious Diseases
سال: 1999
ISSN: 0022-1899,1537-6613
DOI: 10.1086/314721